Classification & Taxonomy

Classification used to be based only on the host of origin; a new classification scheme has been proposed based on the amino acid sequence of Open Reading Frame 2 (this encodes for the capsid polyprotein & has the most variance in the genome).

Family: Astroviridae, Genera: Avastrovirus, Mamastrovirus

They are single stranded, positive sense RNA viruses and are monopartite

They are nonenveloped

The capsid morphology is icosahedral

They are the second or third most common cause of viral diarrhea in young children.

Have been isolated from humans, pigs, cats, minks, sheep, calfs, dogs, bats, rats, deer, and marine mammals such as dolphins and sea lions (these of the Mamastrovirus). Of the Avastrovirus, the virus has been isolated from ducks, chickens, turkeys, and guinea fowl.

Works Cited

“Human Astroviruses.” National Center for Biotechnology Information. U.S. National Library of Medicine, n.d. Web. 19 Mar. 2015.

Knipe, David M., and Bernard N. Fields. “Chapter 21: Astroviridae.” Fields’ Virology. 6th ed. Philadelphia: Lippincott Williams & Wilkins, 2013. 609-28. Print.

“ViralZone: Astroviridae.” ViralZone: Astroviridae. ExPASy, n.d. Web. 19 Mar. 2015.

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